Immunological Studies in Cattle Exposed to Polybrominated Biphenyls

Immunological studies in cattle exposed to polybrominated biphenyls

The intactness of the immune system in cattle exposed to polybrominated biphenyls (PBBs) has been investigated by using several immunoassays. Eighty-seven animals have been studied, 35 control animals (not exposed to PBBs) and 52 animals exposed to PBBs (0.02-30 ppm/g fat equivalent). The immunoassays included a complete blood count, identification of peripheral blood T and B lymphocyte subpopu...

Breast-feeding among women exposed to polybrominated biphenyls in Michigan.

In the early 1970s, the largest industrial accident in the United States resulted in widespread contamination of the food supply in Michigan with polybrominated biphenyls (PBBs). The chemical similarity of PBBs to compounds implicated as endocrine disruptors has raised the question of whether PBBs could affect the reproductive system. In the present analysis we examine the relation between seru...

Neuropsychiatric findings in patients exposed to polybrominated biphenyls.

The inadvertent mixing of polybrominated biphenyls (PBBs) into animal feed in 1973 resulted in the contamination of thousands of Michigan farms. Farm animals who ingested this feed suffered various consequences including weight loss, decreased productivity, frequent infections, skin changes, and reproductive abnormalities.' This error was not initially known, and widespread contamination of hum...

Studies on populations exposed to polychlorinated biphenyls.

Mean serum levels of polychlorinated biphenyls (PCBs) in U.S. population groups without occupational exposure to PCBs are usually between 4 and 8 ng/mL, with 95% of individuals having serum PCB measurements of less than 20. Subpopulations consuming fish taken from contaminated waters, such as Lake Michigan and near Triana, AL, have mean serum PCB levels several times those found in other genera...

Polybrominated biphenyls 74 Hazard assessment of Polybrominated biphenyls